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Yes, you can grow lettuceYes, you can grow lettuce inside year-round, though we'd grow outside when you can. The main requirement is sunlight. Place pots in a bright, sunny south-facing window. In many regions without strong winter sunlight, you'll need to supplement with a combination warm-white/cool-white fluorescent fixture. You'll know if the light is insufficient light because the plants will get leggy and tall.

2015 Special Edition Garden GuideCooking Fresh with The Old Farmer's AlmanacThe Almanac Monthly Digital MagazineWhat the heck is a Garden Hod?